Immobilization Technology
Our polysaccharide-based CSPs, well recognized for their broad range of applications and remarkable loading capacity, are manufactured by physically coating the polysaccharide derivatives onto silica matrices. Using proprietary chemical immobilization technology, the first four polysaccharide-based selectors have been immobilized onto silica.
The CHIRALPAK® IA™, immobilized selector is the tris (3,5-dimethylphenylcarbamate) derivative of amylose.
The CHIRALPAK IB™ selector is the tris (3,5-dimethylphenylcarbamate) derivative of cellulose.
The CHIRALPAK IC™ contains a unique selector, cellulose tris (3,5-dichlorophenylcarbamate), immobilized on silica using proprietary techniques. This selector exhibits a novel chiral molecular recognition mechanism previously unavailable.
The CHIRALPAK ID™ also bears a novel chiral selector, amylose tris (3-chlorophenylcarbamate), immobilized on silica. It is an entirely new molecule and does not correspond to any selectors of the immobilized or coated polysaccharides commercially available.
Immobilization of the polysaccharide derivatives on a matrix provides universal solvent compatibility. This broadens the range of solvents for mobile phases, thereby introducing new selectivity profiles and improved productivity. Virtually any organic solvent can be used in conjunction with these four immobilized CSPs — CHIRALPAK IA, IB, IC or ID. The combination of the broad applicability and high-loading capacity of coated polysaccharide-based CSPs with the universal solvent compatibility of the immobilized CSPs results in a high degree of success in screening for an effective separation method by enantioselective HPLC and SFC.
The immobilized CSPs have been successfully employed in life science research and development applications.
Note: The CHIRALPAK IA and CHIRALPAK IB selectors correspond to the CHIRALPAK AD and CHIRALCEL OD, respectively.
Learn more about Immobilized Polysaccharide CSPs and columns that are available for your separation process.
The CHIRALPAK® IA™, immobilized selector is the tris (3,5-dimethylphenylcarbamate) derivative of amylose.
The CHIRALPAK IB™ selector is the tris (3,5-dimethylphenylcarbamate) derivative of cellulose.
The CHIRALPAK IC™ contains a unique selector, cellulose tris (3,5-dichlorophenylcarbamate), immobilized on silica using proprietary techniques. This selector exhibits a novel chiral molecular recognition mechanism previously unavailable.
The CHIRALPAK ID™ also bears a novel chiral selector, amylose tris (3-chlorophenylcarbamate), immobilized on silica. It is an entirely new molecule and does not correspond to any selectors of the immobilized or coated polysaccharides commercially available.
Immobilization of the polysaccharide derivatives on a matrix provides universal solvent compatibility. This broadens the range of solvents for mobile phases, thereby introducing new selectivity profiles and improved productivity. Virtually any organic solvent can be used in conjunction with these four immobilized CSPs — CHIRALPAK IA, IB, IC or ID. The combination of the broad applicability and high-loading capacity of coated polysaccharide-based CSPs with the universal solvent compatibility of the immobilized CSPs results in a high degree of success in screening for an effective separation method by enantioselective HPLC and SFC.
The immobilized CSPs have been successfully employed in life science research and development applications.
Note: The CHIRALPAK IA and CHIRALPAK IB selectors correspond to the CHIRALPAK AD and CHIRALCEL OD, respectively.
Learn more about Immobilized Polysaccharide CSPs and columns that are available for your separation process.
